/* BiRAGAS Cancer Optimizer v2 - bright, physician & patient facing */
:root{
  --gold:#C9A96A; --gold-deep:#B08D46; --gold-soft:#F3E9D4; --red:#E23A48;
  --navy:#1C2B4C; --ink:#26333f; --slate:#5c6a78; --line:#ece6da;
  --bg:#FFFDF8; --card:#ffffff; --cream:#FBF6EC;
  --teal:#12A6A6; --teal-soft:#E1F5F5; --coral:#F26A5A; --coral-soft:#FDEBE7;
  --violet:#7A5CC0; --violet-soft:#EEEAF9; --green:#2FA36B; --green-soft:#E4F5EC;
  --sky:#2E8BE6; --sky-soft:#E5F0FC;
  --shadow:0 10px 34px rgba(28,43,76,.09); --shadow-sm:0 4px 14px rgba(28,43,76,.07);
  --radius:16px;
}
*{box-sizing:border-box}
html{scroll-behavior:smooth}
body{margin:0;font-family:-apple-system,BlinkMacSystemFont,"Segoe UI",Inter,Roboto,Helvetica,Arial,sans-serif;
  color:var(--ink);background:var(--bg);line-height:1.6;-webkit-font-smoothing:antialiased}
a{color:var(--teal);text-decoration:none} a:hover{text-decoration:underline}
h1,h2,h3,h4{color:var(--navy);line-height:1.15;margin:.2em 0;letter-spacing:-.015em}
img{max-width:100%}
.wrap{max-width:1180px;margin:0 auto;padding:0 22px}
.btn{display:inline-flex;align-items:center;gap:8px;border:none;border-radius:11px;padding:12px 20px;font-weight:700;
  font-size:15px;cursor:pointer;text-decoration:none;transition:.15s}
.btn:hover{text-decoration:none;transform:translateY(-1px)}
.btn-gold{background:linear-gradient(180deg,#D9BC7E,var(--gold-deep));color:#2a2110;box-shadow:0 6px 16px rgba(176,141,70,.35)}
.btn-teal{background:linear-gradient(180deg,#19c0c0,var(--teal));color:#fff;box-shadow:0 6px 16px rgba(18,166,166,.3)}
.btn-ghost{background:#fff;border:1.5px solid var(--line);color:var(--navy)}
.btn-ghost:hover{border-color:var(--gold)}
.btn-sm{padding:8px 13px;font-size:13px;border-radius:9px}

/* header */
header.top{position:sticky;top:0;z-index:50;background:rgba(255,253,248,.92);backdrop-filter:blur(10px);
  border-bottom:1px solid var(--line)}
.top .wrap{display:flex;align-items:center;justify-content:space-between;gap:18px;padding:12px 22px}
.brand{display:inline-flex;align-items:flex-end;gap:3px}
.brand img{height:30px;display:block}
.brand .dot{width:9px;height:9px;border-radius:50%;background:var(--red);margin-bottom:5px}
nav.links{display:flex;align-items:center;gap:6px;flex-wrap:wrap}
nav.links a{color:var(--navy);font-size:14.5px;font-weight:600;padding:8px 12px;border-radius:9px}
nav.links a:hover{background:var(--gold-soft);text-decoration:none}
.navtoggle{display:none;align-items:center;justify-content:center;width:44px;height:44px;flex:0 0 auto;
  background:#fff;border:1.5px solid var(--line);border-radius:11px;color:var(--navy);font-size:22px;line-height:1;cursor:pointer}
.navtoggle:hover{border-color:var(--gold)}
/* keep sticky header from covering anchored sections */
section[id],a#top,#main{scroll-margin-top:80px}

/* hero */
.hero{position:relative;overflow:hidden;
  background:radial-gradient(1200px 500px at 15% -10%,var(--teal-soft),transparent 60%),
             radial-gradient(1000px 460px at 95% 0%,var(--gold-soft),transparent 55%),
             linear-gradient(180deg,#FFFEFB,var(--bg))}
.hero .wrap{padding:64px 22px 40px;display:grid;grid-template-columns:1.15fr .85fr;gap:36px;align-items:center}
.hero .eyebrow{display:inline-block;background:#fff;border:1px solid var(--gold);color:var(--gold-deep);
  font-weight:700;font-size:12.5px;letter-spacing:.04em;text-transform:uppercase;padding:6px 12px;border-radius:999px;box-shadow:var(--shadow-sm)}
.hero h1{font-size:clamp(32px,4.6vw,52px);margin:16px 0 10px}
.hero h1 .hl{color:var(--teal)} .hero h1 .hl2{color:var(--coral)}
.hero p.lead{font-size:19px;color:var(--slate);max-width:600px}
.hero .cta{display:flex;gap:12px;flex-wrap:wrap;margin-top:22px}
.hero .art{background:#fff;border-radius:20px;box-shadow:var(--shadow);border:1px solid var(--line);padding:10px}
.hero .art img{border-radius:14px;display:block}
.hero .art .cap{font-size:12px;color:var(--slate);padding:8px 8px 4px}
.stats{display:flex;flex-wrap:wrap;gap:26px;margin-top:34px;padding:18px 0 6px;border-top:1px dashed var(--line)}
.stats .s b{font-size:26px;color:var(--navy);display:block;line-height:1}
.stats .s span{font-size:13px;color:var(--slate)}

/* generic section */
section{padding:52px 0}
.section-tag{color:var(--teal);font-weight:800;letter-spacing:.06em;text-transform:uppercase;font-size:12.5px}
h2.title{font-size:clamp(26px,3.4vw,36px);margin:6px 0 10px}
.lede{font-size:17px;color:var(--slate);max-width:760px}

/* problem band */
.band{background:linear-gradient(180deg,var(--cream),#fff);border-top:1px solid var(--line);border-bottom:1px solid var(--line)}
.problem-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:18px;margin-top:26px}
.pcell{background:#fff;border:1px solid var(--line);border-radius:var(--radius);padding:22px;box-shadow:var(--shadow-sm)}
.pcell .ic{width:44px;height:44px;border-radius:12px;display:grid;place-items:center;font-size:22px;margin-bottom:12px}

/* ATLAS */
.atlas-head{display:flex;justify-content:space-between;align-items:flex-end;gap:16px;flex-wrap:wrap}
.searchbox{display:flex;align-items:center;gap:8px;background:#fff;border:1.5px solid var(--line);border-radius:12px;padding:8px 12px;min-width:240px}
.searchbox input{border:none;outline:none;font-size:14.5px;width:100%;background:transparent;color:var(--ink)}
.atlas{display:grid;grid-template-columns:262px 1fr;gap:22px;margin-top:22px;align-items:start}
.side{position:sticky;top:76px;max-height:calc(100vh - 96px);overflow-y:auto;background:#fff;border:1px solid var(--line);
  border-radius:var(--radius);padding:12px 10px;box-shadow:var(--shadow-sm)}
.side .gt{font-size:10.5px;font-weight:800;letter-spacing:.05em;text-transform:uppercase;color:var(--gold-deep);margin:12px 8px 5px}
.cat{display:flex;justify-content:space-between;align-items:center;gap:8px;padding:8px 11px;border-radius:10px;cursor:pointer;
  font-size:13.5px;color:var(--navy);font-weight:600}
.cat:hover{background:var(--teal-soft)}
.cat.on{background:var(--navy);color:#fff}
.cat .n{font-size:11px;background:var(--gold-soft);color:var(--gold-deep);border-radius:999px;padding:1px 8px;font-weight:700}
.cat.on .n{background:#ffffff2a;color:#fff}
.main-pane .cat-title{display:flex;align-items:baseline;gap:12px;margin-bottom:4px}
.main-pane .cat-title h3{font-size:22px}
.grid{display:grid;grid-template-columns:repeat(auto-fill,minmax(300px,1fr));gap:18px;margin-top:16px}
.fig{background:#fff;border:1px solid var(--line);border-radius:var(--radius);overflow:hidden;box-shadow:var(--shadow-sm);display:flex;flex-direction:column}
.fig .imgbx{position:relative;background:#fbfaf6;cursor:zoom-in}
.fig .imgbx img{width:100%;display:block;aspect-ratio:16/9;object-fit:cover}
.fig .noimg{aspect-ratio:16/9;display:grid;place-items:center;color:var(--slate);font-size:13px;background:var(--cream)}
.fig .body{padding:14px 15px;display:flex;flex-direction:column;gap:6px;flex:1}
.fig .drug{font-weight:800;color:var(--navy);font-size:15.5px}
.fig .ct{font-size:12.5px;color:var(--slate)}
.fig .mech{font-size:12.5px;color:var(--ink)}
.fig .cite{font-size:11.5px;color:var(--navy)}
.fig .tags{display:flex;flex-wrap:wrap;gap:6px;margin-top:2px}
.tag{font-size:10.5px;font-weight:700;padding:2px 8px;border-radius:999px}
.tag.pat{background:var(--sky-soft);color:var(--sky)}
.tag.cls{background:var(--violet-soft);color:var(--violet)}
.tag.mod{background:var(--green-soft);color:var(--green)}
.fig .dl{display:flex;gap:8px;margin-top:8px;padding-top:10px;border-top:1px dashed var(--line)}

/* why BiRAGAS patterns */
.pattern-grid{display:grid;grid-template-columns:repeat(2,1fr);gap:18px;margin-top:26px}
.pat-card{background:#fff;border:1px solid var(--line);border-left:5px solid var(--teal);border-radius:14px;padding:20px 22px;box-shadow:var(--shadow-sm)}
.pat-card h4{font-size:17px;margin:0 0 4px}
.pat-card .fail{color:var(--teal);font-weight:700;font-size:13px}
.pat-card .fix{color:var(--slate);font-size:14px;margin-top:8px}
.pat-card .fix b{color:var(--navy)}

/* physician CTA */
.cta-band{background:radial-gradient(900px 380px at 90% 0,var(--teal-soft),transparent 60%),linear-gradient(180deg,#fff,var(--cream));
  border-top:1px solid var(--line);border-bottom:1px solid var(--line)}
.cta-grid{display:grid;grid-template-columns:1.1fr .9fr;gap:30px;align-items:center}
.cta-grid ul{list-style:none;padding:0;margin:14px 0 0}
.cta-grid li{padding:7px 0 7px 30px;position:relative;color:var(--ink);font-size:15px}
.cta-grid li::before{content:"✓";position:absolute;left:0;top:6px;width:20px;height:20px;border-radius:50%;background:var(--green-soft);
  color:var(--green);font-weight:800;font-size:12px;display:grid;place-items:center}
.cta-box{background:#fff;border:1px solid var(--line);border-radius:var(--radius);padding:26px;box-shadow:var(--shadow);text-align:center}
.cta-box .big{font-size:20px;color:var(--navy);font-weight:800}

/* downloads */
.dl-grid{display:grid;grid-template-columns:1.3fr .7fr;gap:20px;margin-top:24px}
.dl-card{background:#fff;border:1px solid var(--line);border-radius:var(--radius);padding:24px;box-shadow:var(--shadow-sm);display:flex;gap:18px;align-items:center}
.dl-card .ic{font-size:40px}

/* footer */
footer{background:var(--navy);color:#cdd6e4;padding:36px 0;font-size:13px}
footer a{color:var(--gold)}
footer .wrap{display:grid;grid-template-columns:1.4fr 1fr;gap:24px}
footer .disc{font-size:11.5px;color:#93a0b8;line-height:1.6;margin-top:8px}

/* lightbox */
.lb{position:fixed;inset:0;background:rgba(16,22,34,.9);display:grid;place-items:center;z-index:90;padding:22px}
.lb img{max-width:96vw;max-height:88vh;border-radius:10px;box-shadow:0 20px 60px rgba(0,0,0,.5)}
.lb .cap{color:#fff;text-align:center;margin-top:12px;max-width:800px}
.lb .x{position:absolute;top:18px;right:22px;color:#fff;font-size:30px;cursor:pointer}
.lb .lbdl{display:flex;gap:10px;justify-content:center;margin-top:12px}

.toast{position:fixed;bottom:22px;left:50%;transform:translateX(-50%);background:var(--navy);color:#fff;padding:11px 18px;
  border-radius:11px;font-size:14px;z-index:95;box-shadow:var(--shadow)}
.hidden{display:none!important}

@media(max-width:960px){
  .hero .wrap{grid-template-columns:1fr} .hero .art{max-width:520px;margin:0 auto}
  .atlas{grid-template-columns:1fr}
  .side{position:static;max-height:46vh;overflow-y:auto}
  .problem-grid,.pattern-grid,.cta-grid,.dl-grid,footer .wrap{grid-template-columns:1fr}
}

/* mobile banner: prominent logo + hamburger drawer, page scrolls underneath */
@media(max-width:820px){
  .brand img{height:34px}
  .navtoggle{display:inline-flex}
  nav.links{position:absolute;top:100%;left:0;right:0;flex-direction:column;align-items:stretch;gap:4px;
    background:#FFFDF8;border-bottom:1px solid var(--line);
    padding:10px 16px 16px;box-shadow:var(--shadow);display:none}
  nav.links.open{display:flex}
  nav.links a{font-size:16px;padding:13px 12px;border-radius:10px}
  nav.links a.btn{justify-content:center;margin-top:6px;padding:14px}
}
@media(max-width:640px){
  .wrap{padding:0 16px}
  .top .wrap{padding:10px 16px}
  section{padding:38px 0}
  .hero .wrap{padding:32px 16px 26px;gap:22px}
  .hero p.lead{font-size:16px}
  .stats{gap:14px 24px;margin-top:22px}
  .stats .s b{font-size:22px}
  .pcell,.pat-card,.cta-box,.dl-card{padding:18px}
  .dl-card{flex-direction:column;text-align:center;gap:12px}
  .grid{grid-template-columns:1fr;gap:14px}
  .main-pane .cat-title{flex-wrap:wrap}
  .cat-title .backall{margin-left:0}
  .lb{padding:12px} .lb .x{top:10px;right:14px}
}

/* resistance taxonomy table */
.tax-wrap{overflow-x:auto;margin-top:22px;border:1px solid var(--line);border-radius:var(--radius);box-shadow:var(--shadow-sm);background:#fff}
table.tax{width:100%;border-collapse:collapse;font-size:13.5px;min-width:660px}
table.tax thead th{background:var(--navy);color:#fff;text-align:left;padding:12px 16px;font-size:12.5px;font-weight:700;letter-spacing:.02em}
table.tax thead th:nth-child(2){text-align:center;width:60px}
table.tax tbody td{padding:12px 16px;border-top:1px solid var(--line);vertical-align:top}
table.tax tbody tr:nth-child(even){background:#fcfaf5}
table.tax tbody tr:hover{background:var(--teal-soft)}
.tax .cls{font-weight:800;color:var(--navy);white-space:nowrap}
.tax .n{display:inline-block;min-width:28px;text-align:center;background:var(--gold-soft);color:var(--gold-deep);font-weight:800;border-radius:999px;padding:2px 10px;font-size:12.5px}
.tax .def{color:var(--slate);line-height:1.5}
.tax .cls-link{background:none;border:none;padding:0;font:inherit;font-weight:800;color:var(--teal);cursor:pointer;text-align:left;white-space:nowrap;border-bottom:1.5px dashed transparent}
.tax .cls-link:hover{color:var(--navy);border-bottom-color:var(--gold)}
.pat-filter{background:none;border:none;padding:8px 0 0;margin-top:8px;font:inherit;font-weight:700;font-size:13px;cursor:pointer;text-align:left;border-top:1px dashed var(--line);width:100%}
.pat-filter:hover{filter:brightness(.85);text-decoration:underline}
.cat-title .backall{margin-left:auto;background:#fff;border:1.5px solid var(--line);color:var(--navy);border-radius:9px;padding:7px 13px;font-size:13px;font-weight:700;cursor:pointer;white-space:nowrap}
.cat-title .backall:hover{border-color:var(--gold);background:var(--gold-soft)}